If I can't multiclass into everything I want, I end up spending a day researching all the skills to death, and how they combine with racial skills, general skills, mini skills. Then I built a favorite-to-least-favorite list. Then I spend a couple hours grumping to close friends about how I wish I could have them all. Then I roll the class I ended up picking that had the least overlap of skills with other skills + looked cool and fun and was my favorite thematically. Then I plot how I'll multiclass and what classes I'd pick next based off of character motivations and interests and skills and overlap.
Short of making everyone able to just swap genders whenever they decide to identify one way or the other, I think the best option most people will find (based off of what's consistent with most IRE games) is to just pick the Sex that their character identifies with as their gender.
Maybe there will be a 'they' option, as a third choice, to provide neutral as a pick. Dunno, just depends on how developed the code is in that area and whether they can inject such a thing in there with nothing breaking.
We have to keep in mind that any change they make to already existing software can, and likely will, break something. That is pretty much a given in anything IT related, and that only pushes the release further back. Worst case (short of it just being scrapped) is that it'd have to be pushed back, and provided as a free-change sort of thing at some point.